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1

Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells

Hirohashi, Yoshihiko, Torigoe, Toshihiko, Inoda, Satoko, Takahashi, Akari, Morita, Rena, Nishizawa, Satoshi, Tamura, Yasuaki, Suzuki, Hiromu, Toyota, Minoru, Sato, Noriyuki

Journal:

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

2

High expression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cell carcinomas correlates to lymph node metastasis

Yoshitaka Michifuri, Yoshihiko Hirohashi, Toshihiko Torigoe, Akihiro Miyazaki, Junichi Kobayashi, Takanori Sasaki, Jyunki Fujino, Hiroko Asanuma, Yasuaki Tamura, Kenji Nakamori, Tadashi Hasegawa, Hiro

Journal:

Pathology International

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

3

The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer

Miyamoto, Sho, Kochin, Vitaly, Kanaseki, Takayuki, Hongo, Ayumi, Tokita, Serina, Kikuchi, Yasuhiro, Takaya, Akari, Hirohashi, Yoshihiko, Tsukahara, Tomohide, Terui, Takeshi, Ishitani, Kunihiko, Hata,

Journal:

Cancer Immunology Research

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

4

Identification of human antitumor cytotoxic T lymphocytes epitopes of recoverin, a cancer-associated retinopathy antigen, possibly related with a better prognosis in a paraneoplastic syndrome

Akiko Maeda, Hiroshi Ohguro, Yuki Nabeta, Yoshihiko Hirohashi, Hiroeki Sahara, Tadao Maeda, Yoshimasa Wada, Takashi Sato, Chyuns Yun, Yasuharu Nishimura, Toshihiko Torigoe, Yoshio Kuroki, Noriyuki Sat

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

5

Efficacy of preoperative portal vein embolization prior to major hepatectomy for patients with impaired liver function: A retrospective study

Shoji Kubo, Hiroaki Kinoshita, Kazuhiro Hirohashi, Hiromu Tanaka, Tadashi Tsukamoto, Taichi Shuto, Yoshihiko Morimoto, Akishige Kanazawa, Shinichi Mikami, Chikaharu Sakata

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

1997

Language:

english

File:

PDF, 451 KB

english, 1997

6

Frequent detection of anti-recoverin cytotoxic T-lymphocyte precursors in peripheral blood of cancer patients by using an HLA-Aff24-recoverin tetramer

Shunshui Rong, Hideyuki Ikeda, Yuriko Sato, Yoshihiko Hirohashi, Yukio Takamura, Hiroeki Sahara, Takashi Sato, Akiko Maeda, Hiroshi Ohguro, Noriyuki Sato

Journal:

Cancer Immunology, Immunotherapy

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

7

Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer

Ichiya Honma, Hiroshi Kitamura, Toshihiko Torigoe, Akari Takahashi, Toshiaki Tanaka, Eiji Sato, Yoshihiko Hirohashi, Naoya Masumori, Taiji Tsukamoto, Noriyuki Sato

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

8

Interferon γ assay for detecting latent tuberculosis infection in rheumatoid arthritis patients during infliximab administration

Hiroki Takahashi, Katsunori Shigehara, Motohisa Yamamoto, Chisako Suzuki, Yasuyoshi Naishiro, Yasunori Tamura, Yoshihiko Hirohashi, Noriyuki Satoh, Noriharu Shijubo, Yasuhisa Shinomura, Kohzoh Imai

Journal:

Rheumatology International

Year:

2007

Language:

english

File:

PDF, 310 KB

english, 2007

9

Autoantibody against hypoxia-inducible factor prolyl hydroxylase-3 is a potential serological marker for renal cell carcinoma

Toshiaki Tanaka, Hiroshi Kitamura, Toshihiko Torigoe, Yoshihiko Hirohashi, Eiji Sato, Naoya Masumori, Noriyuki Sato, Taiji Tsukamoto

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 335 KB

english, 2011

10

Recognition by cellular and humoral autologous immunity in a human osteosarcoma cell line

Yuki Nabeta, Satoshi Kawaguchi, Hiroeki Sahara, Hideyuki Ikeda, Yoshihiko Hirohashi, Takahiro Goroku, Yuriko Sato, Tomohide Tsukahara, Toshihiko Torigoe, Takuro Wada, Mitsunori Kaya, Hiroaki Hiraga, K

Journal:

Journal of Orthopaedic Science

Year:

2003

Language:

english

File:

PDF, 214 KB

english, 2003

11

Polypoid endometriosis of the ureter mimicking fibroepithelial polyps

Nagaaki Marugami, Shinji Hirohashi, Satoru Kitano, Junko Takahama, Takahiro Ito, Kazumasa Torimoto, Yoshihiko Hirao, Kimihiko Kichikawa

Journal:

Japanese Journal of Radiology

Year:

2008

Language:

english

File:

PDF, 335 KB

english, 2008

12

Disruption of the association of 73 kDa heat shock cognate protein with transporters associated with antigen processing (TAP) decreases TAP-dependent translocation of antigenic peptides into the endoplasmic reticulum

Kenjiro Kamiguchi, Toshihiko Torigoe, Osamutaro Fujiwara, Shin Ohshima, Yoshihiko Hirohashi, Hiroeki Sahara, Itaru Hirai, Yutaka Kohgo, Noriyuki Sato

Journal:

Microbiology and Immunology

Year:

2008

Language:

english

File:

PDF, 752 KB

english, 2008

13

Induction of Cytotoxic T Lymphocytes from Peripheral Blood of Human Histocompatibility Antigen (HLA)-A31+ Gastric Cancer Patients by in vitro Stimulation with Antigenic Peptide of Signet Ring Cell Carcinoma

Yuki Nabeta, Hiroeki Sahara, Kazuhiro Suzuki, Hiroaki Kondo, Masami Nagata, Yoshihiko Hirohashi, Yuriko Sato, Yoshimasa Wada, Takashi Sato, Takuro Wada, Toshihiko Yamashita, Kokichi Kikuchi, Noriyuki

Journal:

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

14

Natural Antigenic Peptides from Squamous Cell Carcinoma Recognized by Autologous HLA-DR8–restricted CD4+ T Cells

Hiroaki Kondo, Hiroeki Sahara, Akihiro Miyazaki, Yuki Nabeta, Yoshihiko Hirohashi, Takayuki Kanaseki, Akira Yamaguchi, Naoyuki Yamada, Kazuo Hirayama, Manabu Suzuki, Junji Hamuro, Toshihiko Torigoe, N

Journal:

Year:

2002

Language:

english

File:

PDF, 144 KB

english, 2002

15

The functioning antigens: beyond just as the immunological targets

Yoshihiko Hirohashi, Toshihiko Torigoe, Satoko Inoda, Jun–ichi Kobayasi, Munehide Nakatsugawa, Takashi Mori, Isao Hara, Noriyuki Sato

Journal:

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

16

Novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4

Munehide Nakatsugawa, Yoshihiko Hirohashi, Toshihiko Torigoe, Hiroko Asanuma, Akari Takahashi, Satoko Inoda, Kenji Kiriyama, Emiri Nakazawa, Kenji Harada, Hideo Takasu, Yasuaki Tamura, Kenjiro Kamiguc

Journal:

Year:

2009

Language:

english

File:

PDF, 2.64 MB

english, 2009

17

Human leukocyte antigen class I down-regulation in muscle-invasive bladder cancer: Its association with clinical characteristics and survival after cystectomy

Ichiya Homma, Hiroshi Kitamura, Toshihiko Torigoe, Toshiaki Tanaka, Eiji Sato, Yoshihiko Hirohashi, Naoya Masumori, Noriyuki Sato, Taiji Tsukamoto

Journal:

Year:

2009

Language:

english

File:

PDF, 292 KB

english, 2009

18

Phase I clinical trial of survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer

Akihiro Miyazaki, Junichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Takashi Yamamoto, Akira Yamaguchi, Hiroko Asanuma, Akari Takahashi, Yoshitaka Michifuri, Kenji Nakamori, Itaru Nagai, Noriy

Journal:

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

19

Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients

Hidekazu Kameshima, Tetsuhiro Tsuruma, Toshihiko Torigoe, Akari Takahashi, Yoshihiko Hirohashi, Yasuaki Tamura, Tomohide Tsukahara, Shingo Ichimiya, Takayuki Kanaseki, Yuji Iwayama, Noriyuki Sato, Koi

Journal:

Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

20

CYP3A induction aggravates endotoxemic liver injury via reactive oxygen species in male rats

Yukiko Minamiyama, Shigekazu Takemura, Shinya Toyokuni, Susumu Imaoka, Yoshihiko Funae, Kazuhiro Hirohashi, Toshikazu Yoshikawa, Shigeru Okada

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 739 KB

english, 2004

21

DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription

Xiulian Du, Qiang Wang, Yoshihiko Hirohashi, Mark I. Greene

Journal:

Experimental and Molecular Pathology

Year:

2006

Language:

english

File:

PDF, 561 KB

english, 2006

22

Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells

Yoshihiko Hirohashi, Toshihiko Torigoe, Itaru Hirai, Yasuaki Tamura, Munehide Nakatsugawa, Yuuji Inoue, Takayuki Kanaseki, Kenjiro Kamiguchi, Hideyuki Ikeda, Aya Sasaki, Noboru Yamanaka, Noriyuki Sato

Journal:

Experimental and Molecular Pathology

Year:

2010

Language:

english

File:

PDF, 440 KB

english, 2010

23

Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: A mechanism for aneuploidy in cancer

Qingdu Liu, Yoshihiko Hirohashi, Xiulian Du, Mark I. Greene, Qiang Wang

Journal:

Experimental and Molecular Pathology

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

24

The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma

Satoko Inoda, Rena Morita, Yoshihiko Hirohashi, Toshihiko Torigoe, Hiroko Asanuma, Emiri Nakazawa, Munehide Nakatsugawa, Yasuaki Tamura, Kenjiro Kamiguchi, Tetsuhiro Tsuruma, Takeshi Terui, Kunihiko I

Journal:

Experimental and Molecular Pathology

Year:

2011

Language:

english

File:

PDF, 994 KB

english, 2011

25

Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population

Takashi Mori, Satoshi Nishizawa, Yoshihiko Hirohashi, Toshihiko Torigoe, Yasuaki Tamura, Akari Takahashi, Vitaly Kochin, Reona Fujii, Toru Kondo, Mark I. Greene, Isao Hara, Noriyuki Sato

Journal:

Experimental and Molecular Pathology

Year:

2012

Language:

english

File:

PDF, 469 KB

english, 2012

26

Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses

Masahito Mizuuchi, Yoshihiko Hirohashi, Toshihiko Torigoe, Takafumi Kuroda, Kazuyo Yasuda, Yoshitaka Shimizu, Tsuyoshi Saito, Noriyuki Sato

Journal:

Experimental and Molecular Pathology

Year:

2012

Language:

english

File:

PDF, 337 KB

english, 2012

27

Improved generation of HLA class I/peptide tetramers

Yuriko Sato, Hiroeki Sahara, Tomohide Tsukahara, Masako Kondo, Yoshihiko Hirohashi, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Toshihiko Torigoe, Shingo Ichimiya, Yasuaki Tamura, Takuro Wada, Tos

Journal:

Journal of Immunological Methods

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

28

Immunohistochemical and Immunoblot Analyses of ras-p21 Expression in Lung Carcinomas

Yoshihiko Koshiishi, Masayuki Noguchi, Takashi Nakajima, Setsuo Hirohashi, Yukio Shimosato, Yoshihiro Hayata

Journal:

Pathology International

Year:

1989

Language:

english

File:

PDF, 540 KB

english, 1989

29

Molecular pathological approaches to human tumor immunology

Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Tomoki Kikuchi, Hiroeki Sahara, Kenjiro Kamiguchi, Shingo Ichimiya, Yasuaki Tamura, Toshihiko Torigoe

Journal:

Pathology International

Year:

2009

Language:

english

File:

PDF, 875 KB

english, 2009

30

Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue: Unusually high frequency of down-regulation in breast cancer tissues

Toshihiko Torigoe, Hiroko Asanuma, Emiri Nakazawa, Yasuaki Tamura, Yoshihiko Hirohashi, Eri Yamamoto, Takayuki Kanaseki, Tadashi Hasegawa, Noriyuki Sato

Journal:

Pathology International

Year:

2012

Language:

english

File:

PDF, 858 KB

english, 2012

31

Cytotoxic T Lymphocytes Efficiently Recognize Human Colon Cancer Stem-Like Cells

Satoko Inoda, Yoshihiko Hirohashi, Toshihiko Torigoe, Rena Morita, Akari Takahashi, Hiroko Asanuma, Munehide Nakatsugawa, Satoshi Nishizawa, Yasuaki Tamura, Tetsuhiro Tsuruma, Takeshi Terui, Toru Kond

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

32

Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma

Jun-Ichi Kobayashi, Yoshihiko Hirohashi, Toshihiko Torigoe, Yoshitaka Michifuri, Takashi Yamamoto, Yasuaki Tamura, Kenjiro Kamiguchi, Akihiro Miyazaki, Akira Yamaguchi, Hiroyuki Hariu, Hiroyoshi Hirat

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 652 KB

english, 2009

33

Recovery of Hepatic Function Determined by Cytochrome P450-Dependent Drug Metabolism Lags After Compensatory Hepatic Volume Changes After Portal Vein Ligation in Rats

Shigekazu Takemura, Yukiko Minamiyama, Kazuhiro Hirohashi, Shoji Kubo, Yoshihiko Funae, Hiroaki Kinoshita

Journal:

Journal of Surgical Research

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

34

Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: Implications for specific immunotherapy

Hiroshi Kitamura, Toshihiko Torigoe, Ichiya Honma, Hiroko Asanuma, Emiri Nakazawa, Kumiko Shimozawa, Yoshihiko Hirohashi, Eiji Sato, Noriyuki Sato, Taiji Tsukamoto

Journal:

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

35

Expression of Livin in Renal Cell Carcinoma and Detection of Anti-livin Autoantibody in Patients

Hiroshi Kitamura, Ichiya Honma, Toshihiko Torigoe, Hiroyuki Hariu, Hiroko Asanuma, Yoshihiko Hirohashi, Eiji Sato, Noriyuki Sato, Taiji Tsukamoto

Journal:

Year:

2007

Language:

english

File:

PDF, 838 KB

english, 2007

36

Overexpression of CYP3A aggravates endotoxin-induced liver injury in hypophysectomized female rats

Shigekazu Takemura, Yukiko Minamiyama, Shinya Toyokuni, Susumu Imaoka, Seikan Hai, Shoji Kubo, Kazuhiro Hirohashi, Yoshihiko Funae, Shigeru Okada

Journal:

Hepatology Research

Year:

2008

Language:

english

File:

PDF, 505 KB

english, 2008

37

Gene Expression Profiles of Prostate Cancer Stem Cells Isolated by Aldehyde Dehydrogenase Activity Assay

Nishida, Sachiyo, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Kitamura, Hiroshi, Takahashi, Akari, Masumori, Naoya, Tsukamoto, Taiji, Sato, Noriyuki

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

38

432 A NOVEL TUMOR-ASSOCIATED ANTIGEN, DNAJB8 IS HIGHLY EXPRESSED IN CANCER STEM-LIKE CELLS/CANCER-INITIATING CELLS OF RENAL CELL CARCINOMA, AND IS POTENT TARGET FOR IMMUNOTHERAPY

Nishizawa, Satoshi, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Matsumura, Nagahide, Inagaki, Takeshi, Kohjimoto, Yasuo, Sato, Noriyuki, Hara, Isao

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 103 KB

english, 2012

39

Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia

Shigekazu Takemura, Yukiko Minamiyama, Susumu Imaoka, Yoshihiko Funae, Kazuhiro Hirohashi, Masayasu Inoue, Hiroaki Kinoshita

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 1.13 MB

english, 1999

40

Nuclear, but not cytoplasmic, localization of survivin as a negative prognostic factor for survival in upper urinary tract urothelial carcinoma

Kitamura, Hiroshi, Torigoe, Toshihiko, Hirohashi, Yoshihiko, Asanuma, Hiroko, Inoue, Ryuta, Nishida, Sachiyo, Tanaka, Toshiaki, Masumori, Naoya, Sato, Noriyuki, Tsukamoto, Taiji

Journal:

Virchows Archiv

Year:

2013

Language:

english

File:

PDF, 379 KB

english, 2013

41

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

Akari Takahashi, Toshihiko Torigoe, Yasuaki Tamura, Takayuki Kanaseki, Tomohide Tsukahara, Yasushi Sasaki, Hidekazu Kameshima, Tetsuhiro Tsuruma, Koichi Hirata, Takashi Tokino, Yoshihiko Hirohashi, No

Journal:

Cell Stress and Chaperones

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

42

Detection of autoantibodies to livin and survivin in Sera from lung cancer patients

Yagihashi, Atsuhito, Asanuma, Koichi, Kobayashi, Daisuke, Tsuji, Naoki, Shijubo, Yasuharu, Abe, Shosaku, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Sato, Noriyuki, Watanabe, Naoki

Journal:

Year:

2005

Language:

english

File:

PDF, 110 KB

english, 2005

43

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Kutomi, Goro, Shima, Hiroaki, Iwayama, Yuji, Kimura, Yasutoshi, Imamura, Masahumi, Torigoe, Toshihiko, Takahashi, Akari, Hirohashi, Yoshihiko, Tamura, Yasuaki,

Journal:

Year:

2013

Language:

english

File:

PDF, 305 KB

english, 2013

44

Histopathology of the pancreas in fulminant type 1 diabetes after 23-year follow-up: a case report

Sato, Tatsuya, Miki, Takayuki, Murakami, Naoto, Hirohashi, Yoshihiko, Kouzu, Hidemichi, Furuhashi, Masato, Tanno, Masaya, Yuda, Satoshi, Saitoh, Shigeyuki, Hasegawa, Tadashi, Miura, Tetsuji

Journal:

Pathology International

Year:

2012

Language:

english

File:

PDF, 567 KB

english, 2012

45

Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer

Ichiya Honma, Toshihiko Torigoe, Yoshihiko Hirohashi, Hiroshi Kitamura, Eiji Sato, Naoya Masumori, Yasuaki Tamura, Taiji Tsukamoto, Noriyuki Sato

Journal:

Journal of Translational Medicine

Year:

2009

Language:

english

File:

PDF, 1.93 MB

english, 2009

46

Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients

Jun-ichi Kobayashi, Toshihiko Torigoe, Yoshihiko Hirohashi, Satomi Idenoue, Akihiro Miyazaki, Akira Yamaguchi, Hiroyoshi Hiratsuka, Noriyuki Sato

Journal:

Journal of Translational Medicine

Year:

2009

Language:

english

File:

PDF, 1.79 MB

english, 2009

47

Use of potassium channel tetramerization domain-containing 12 as a biomarker for diagnosis and prognosis of gastrointestinal stromal tumor

Hasegawa, Tadashi, Asanuma, Hiroko, Ogino, Jiro, Hirohashi, Yoshihiko, Shinomura, Yasuhisa, Iwaki, Hiroyuki, Kikuchi, Hironobu, Kondo, Tadashi

Journal:

Human Pathology

Year:

2013

Language:

english

File:

PDF, 765 KB

english, 2013

48

Cytotoxic T lymphocytes: the future of cancer stem cell eradication?

Saijo, Hiroshi, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Kochin, Vitaly, Takahashi, Hiroki, Sato, Noriyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 516 KB

english, 2013

49

Tumor-associated dendritic cells: molecular mechanisms to suppress antitumor immunity

Hirohashi, Yoshihiko, Sato, Noriyuki

Journal:

Year:

2011

Language:

english

File:

PDF, 324 KB

english, 2011

50

Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication

Yamamoto, Takashi, Tamura, Yasuaki, Kobayashi, Jun-ichi, Kamiguchi, Kenjirou, Hirohashi, Yoshihiko, Miyazaki, Akihiro, Torigoe, Toshihiko, Asanuma, Hiroko, Hiratsuka, Hiroyoshi, Sato, Noriyuki

Journal:

Experimental Cell Research

Year:

2013

Language:

english

File:

PDF, 2.34 MB

english, 2013